The IH2A chair brings together academic researchers, clinicians, industrials, therapists and users to develop innovative, easy to use, accessible for everyone assistive solutions. The various stakeholders coordinate their efforts with an iterative and transdisciplinary approach from the emergence of the need to clinical evaluation with end-users and ecological tests in real-life condiitions. During the co-design process, the technology is first evaluated to validate its effectiveness and reliability, and then, the close collaboration between researchers and clinicians within the chair makes it possible to move to the clinical and ecological trials stage to prove efficiency and assess the clinical and societal benefits of use. Tests with end-users in the reproduction of everyday or leisure situations (navigation with a power wheelchair, adapted sports, visits to heritage sites, etc.) are performed to assess the scientific interest and performance of the proposed technologies (robustness, energy consumption, etc.), but also to measure outcomes such as the assistance and safety levels brought by an assistive solutions, the fidelity of multi-sensory simulators, the accessibility of public facilities, etc.